Effects of selective serotonin reuptake inhibitors on motor neuron survival

Selective Serotonin Reuptake Inhibitors

It has long been postulated that a deficiency in CNS serotonergic activity is the cause of, or a predisposing factor for, depression. [1] However, the evidence for this association is largely circumstantial and it certainly does not represent an adequate and full model for depression, probably due to there being multiple aetiological factors. [2] Some pharmacological trial data also cast doubt ...

Selective serotonin reuptake inhibitors.

Treatment of selective mutism: focus on selective serotonin reuptake inhibitors.

Abstract Selective mutism is a pediatric psychiatric disorder that occurs when a child consistently fails to speak in specific situations in which speaking is expected, such as at school and social gatherings, but speaks appropriately in other settings. Selective mutism often is diagnosed when a child starts school and does not talk to teachers or peers, but talks to family members at home; the...

Cerebrovascular effects of selective serotonin reuptake inhibitors: a systematic review.

OBJECTIVES An understanding of cerebro-vascular effects of selective serotonin reuptake inhibitors (SSRIs) is essential, since SSRIs are a widely used antidepressant, serotonin is a vasoactive and thrombostatic amine, and there is a bidirectional relationship between depression and cerebrovascular disease. DATA SOURCES A MEDLINE search was performed to identify published reports over the peri...

Emotional side-effects of selective serotonin reuptake inhibitors: qualitative study.

BACKGROUND Some people who take selective serotonin reuptake inhibitor (SSRI) antidepressants report that their experience of emotions is 'blunted'. This phenomenon is poorly understood. AIMS To understand patients' experiences of this phenomenon. METHOD Qualitative study, gathering data through individual interviews, a group interview and validation interviews; and searching patient websit...